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GFR Information


This test is designed to measure the Glomerular Filtration Rate (GFR) which indicates how well the kidneys filter and remove unwanted substances from the blood.

This test is performed to monitor renal function for a number of reasons including:

  • Assessment of potential live kidney donors for transplantation
  • Pre & post therapy monitoring
  • Evaluation of single kidney function, in conjunction with relative renal function measurements from static or dynamic radionuclide
  • Evaluation and follow up of renal function in chronic glomerulonephropathies e.g. haemolytic uraemic syndrome or diabetes mellitus.
  • Detection of renal failure where:
    (a) Serum creatinine results may be misleading
    (b) Missing a decline in renal function may be serious, such as: single kidney, renovascular disease or renal transplant
    (c) 24 hr clearance measurement is difficult

GFR Assessment

Patients are injected with 99mTc-DTPA, which is cleared from the blood via the glomeruli within the kidneys. Blood samples are collected 2 and 4 hours later and the level of 99mTc-DTPA remaining is measured using a gamma counter. From this members of our team can calculate the GFR.

Patient Preparation

Prior to your appointment you must not have any caffeine, this includes; tea, coffee, chocolate, energy drinks and fizzy drinks, from whenyou wake up on the day of your test.

If you have been referred to our department for a GFR assessment, please feel free to download the patient information sheet below.

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Last updated - 16 August 2019
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Queen Alexandra Hospital
Cosham, Portsmouth
Tel: 023 9228 6000

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